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CCU109: Inequalities in non-ST elevation myocardial infarction care during the COVID-19 pandemic for people living with chronic kidney disease and frailty

Reference: CCU109

Project lead(s): Patrick Bidulka, London School of Hygiene & Tropical Medicine

Start date:

Topic(s):

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CCU104: Neurological consequences of COVID-19: impact of the COVID-19 pandemic on stroke and dementia in England

Reference: CCU104

Project lead(s): Eric Harshfield, University of Cambridge

Start date:

Topic(s):

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CCU103: Healthcare utilisation of patients with atrial fibrillation in England pre and post COVID-19 pandemic

Reference: CCU103

Project lead(s): Rui Providencia, University College London

Start date:

Topic(s):

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CCU099: Cardiovascular disease and cancer screening, and heart failure diagnosis and mortality in people with severe or complex mental illness: the impact of the COVID-19 pandemic

Reference: CCU099

Project lead(s): Naomi Launders, University College London

Start date:

Topic(s):

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CCU070: Supporting novel trial designs using healthcare systems data to mitigate the impact of COVID-19 on diabetes research

Reference: CCU070

Project lead(s): Marion Mafham

Start date:

Topic(s): Clinical trials, Diabetes, Healthcare delivery

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CCU106: Impact of the COVID-19 pandemic on cardiovascular risk in patients with and without kidney disease

Reference: CCU106

Project lead(s): Gavin Chapman, University of Edinburgh

Start date:

Topic(s): Healthcare delivery, Inequalities, Kidneys

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CCU105: Health inequality in the incidence and clinical outcomes of chronic kidney disease following myocardial infarction: investigating the impact of the COVID-19 pandemic through whole-population analyses

Reference: CCU105

Project lead(s): Marlous Hall, University of Leeds

Start date:

Topic(s): Healthcare delivery, Heart attack, Inequalities, Kidneys, Myocardial infarction, Whole population

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Active

CCU101: Lung-Pal-Equity: To identify patterns in use of hospital services in the last year of life for those with advanced lung disease and to examine inequalities by socio-economic group, before, during and after the COVID-19 pandemic

Reference: CCU101

Project lead(s): Donna Wakefield & Joanna Davies, King's College London

Start date:

Topic(s): Healthcare delivery, Inequalities, Lungs, Prediction

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CCU100: Impact of COVID-19 on fatty liver disease and cardiovascular outcomes in England, across ethnicities and social deprivation

Reference: CCU100

Project lead(s): Mayank Dalakoti, Angela Wood, Emanuele Di Angelantonio, University of Cambridge

Start date:

Topic(s): Inequalities, Multiple conditions, Whole population

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CCU097: Drivers, consequences and the COVID-19 pandemic’s effect on severe hyperglycaemia at type 2 diabetes diagnosis

Reference: CCU097

Project lead(s): Ewan A Walker & Rachel Denholm, University of Bristol, and Sophie Eastwood, University College London

Start date:

Topic(s): Diabetes, Healthcare delivery, Prediction, Whole population

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CCU095: Quantifying and mitigating bias and health inequalities induced by clinical risk models

Reference: CCU095

Project lead(s): Honghan Wu, University College London

Start date:

Topic(s): Artificial intelligence, Healthcare delivery, Inequalities, Model, Prediction, Whole population

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CCU094: Identifying preventative opportunities for coronary heart disease and stroke in multi-ethnic patients with non-cardiovascular conditions including COVID-19

Reference: CCU094

Project lead(s): Elias Allara, University of Cambridge

Start date:

Topic(s): Coronary heart disease, Inequalities, Stroke

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Active

CCU093: Understanding the relationship between diabetes and the development of multiple long-term conditions, during and after the COVID-19 pandemic

Reference: CCU093

Project lead(s): Genevieve Cezard, University of Cambridge

Start date:

Topic(s): Diabetes, Inequalities, Multiple conditions, Whole population

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Active

CCU096: Impact of COVID-19 on obesity and risks of cardio-renal-metabolic outcomes

Reference: CCU096

Project lead(s): Robert Fletcher, Angela Wood & Sadaf Farooqi, University of Cambridge, Reecha Sofat, University of Liverpool, Nathalie Conrad, KU Leuven

Start date:

Topic(s): Healthcare delivery, Inequalities, Kidneys, Multiple conditions, Treatments, Whole population

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CCU092: Simulation modelling of cardiovascular disease development and management

Reference: CCU092

Project lead(s): Lois Kim, University of Cambridge

Start date:

Topic(s): Healthcare delivery, Inequalities, Model

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CCU090: The impact of cardiac rehabilitation following transcatheter aortic valve implantation (TAVI) before and after the COVID-19 pandemic

Reference: CCU090

Project lead(s): Justin Braver & Angela Wood, University of Cambridge

Start date:

Topic(s): Healthcare delivery, Treatments, Whole population

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CCU089: The impact of comorbidity, socioeconomic status, and ethnicity on waiting times for surgery before and after the COVID-19 pandemic

Reference: CCU089

Project lead(s): Antony Palmer, University of Oxford

Start date:

Topic(s): Inequalities, Multiple conditions, Treatments

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CCU088: The impact of COVID-19 on the management of iron deficiency (with or without anaemia) in primary and secondary care

Reference: CCU088

Project lead(s): Akshay Shah, University of Oxford

Start date:

Topic(s): Healthcare delivery, Inequalities, Treatments

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Active

CCU087: The impact of COVID-19 on heart failure outcomes: the moderation roles of diabetes and obesity

Reference: CCU087

Project lead(s): Ewan Pearson, University of Dundee

Start date:

Topic(s): Diabetes, Heart failure, Inequalities, Multiple conditions, Whole population

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CCU086: A data landscape review of datasets used in the surveillance of neurological complications of COVID-19

Reference: CCU086

Project lead(s): Stephen McKeever, University of Liverpool

Start date:

Topic(s): Healthcare delivery, Multiple conditions

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CCU080: Impact of COVID-19 on the use of cardiovascular imaging

Reference: CCU080

Project lead(s): Michelle Williams, University of Edinburgh

Start date:

Topic(s): Imaging, Inequalities, Whole population

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CCU085: STROKE-IMPACT: What are the long-term consequences of stroke on the patient and to the NHS, and how does COVID-19 contribute to variation?

Reference: CCU085

Project lead(s): Michael Allen, University of Exeter

Start date:

Topic(s): Healthcare delivery, Inequalities, Stroke

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CCU084: Impact of COVID-19 on stroke incidence, severity, aetiology, management and outcome in younger vs. older individuals in England

Reference: CCU084

Project lead(s): Linxin Li, University of Oxford

Start date:

Topic(s): Healthcare delivery, Inequalities, Stroke

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CCU083: Trends in choice of management strategy for NSTE-ACS among patients with previous bypass surgery before and after the COVID-19 pandemic

Reference: CCU083

Project lead(s): Mohamed Mohamed, Barts Heart Centre/University College London & Krishnaraj Rathod/ Daniel Jones, Barts Heart Centre/Queen Mary University London

Start date:

Topic(s): Healthcare delivery, Heart attack, Inequalities, Treatments, Whole population

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Active

CCU082: Pulmonary arterial hypertension in repaired congenital heart disease: Impact of the COVID-19 pandemic on prevalence, late diagnosis and outcomes

Reference: CCU082

Project lead(s): Andrew Constantine, Royal Brompton Hospital/Imperial College London

Start date:

Topic(s): Blood pressure, Congenital heart disease, Hypertension, Prediction

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Active

CCU077: Risk assessment and long-term outcomes of acute coronary syndrome management strategy in cardio-oncology patients before and after the COVID era

Reference: CCU077

Project lead(s): Mohamed Mohamed & Amitava Banerjee, University College London

Start date:

Topic(s): Cancer, Healthcare delivery, Multiple conditions, Treatments

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CCU081: Investigating the impact of COVID-19 on cardiovascular and thromboembolic events in idiopathic inflammatory myopathies and the incidence of connective tissue diseases

Reference: CCU081

Project lead(s): Hector Chinoy, University of Manchester

Start date:

Topic(s): Blood clots, COVID vaccination, Rare diseases, Thrombosis, Treatments

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Active

CCU079: Investigating the diagnoses of conditions among children in England following SARS-CoV-2 infections compared to general respiratory infections

Reference: CCU079

Project lead(s): Katharine Looker & Eleanor Walsh, University of Bristol

Start date:

Topic(s): Children and young people, Long COVID, Lungs, Multiple conditions, Whole population

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Active

CCU078: Foresight: a generative AI model of patient trajectories across the COVID-19 pandemic

Reference: CCU078

Project lead(s): Richard Dobson, King's College London & Chris Tomlinson, University College London

Start date:

Topic(s): Artificial intelligence, Inequalities, Model, Multiple conditions, Prediction, Whole population

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Active

CCU057: Risks for mortality in people with severe mental illnesses during the COVID-19 pandemic

Reference: CCU057

Project lead(s): Jayati Das-Munshi, King's College London

Start date:

Topic(s): Healthcare delivery, Inequalities, Mental health, Multiple conditions

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CCU074: Improving the accuracy, equity and efficiency of using healthcare systems data for recruitment to a clinical trial involving people with cardiovascular diseases and diabetes mellitus: a simulation study in the “Covid era” using the CVD‑COVID‑UK dataset

Reference: CCU074

Project lead(s): Alice Hosking, University of Edinburgh

Start date:

Topic(s): Clinical trials, Diabetes, Inequalities, Multiple conditions, Stroke

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Active

CCU058: COVID-19 impact on the long-term outcomes of IAPT in people with long-term cardiovascular conditions

Reference: CCU058

Project lead(s): Alex Dregan, King's College London

Start date:

Topic(s): Healthcare delivery, Mental health, Treatments

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CCU059: Which combinations of Multiple Long-Term Conditions (MLTC) are associated with the greatest risk of hospital admission over the winter season, and to what extent does COVID-19 or influenza vaccination modify this risk?

Reference: CCU059

Project lead(s): Nazrul Islam & Hajira Dambha-Miller, University of Southampton

Start date:

Topic(s): COVID vaccination, Healthcare delivery, Multiple conditions, Whole population, Winter pressures

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CCU076: The effect of COVID-19 infection on cardiovascular outcomes: an interaction analysis with environmental exposure

Reference: CCU076

Project lead(s): Elena Raffetti & Angela Wood, University of Cambridge, Rachel Denholm, University of Bristol

Start date:

Topic(s): Environment, Healthcare delivery, Winter pressures

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Active

CCU075: Impact of the COVID-19 pandemic on corticosteroid use and side effects in Takayasu arteritis and ANCA-associated vasculitis in England

Reference: CCU075

Project lead(s): Stephanie Lax, University of Nottingham

Start date:

Topic(s): Healthcare delivery, Inequalities, Rare diseases, Treatments

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Active

CCU071: A regional approach for policy makers to tackle health inequalities in cardiovascular disease and its risk factors

Reference: CCU071

Project lead(s): Reecha Sofat, University of Liverpool

Start date:

Topic(s): Inequalities, Treatments

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CCU060: Improving characterisation, prediction and intervention for COVID- and influenza-related morbidity and mortality

Reference: CCU060

Project lead(s): Amitava Banerjee, University College London

Start date:

Topic(s): Healthcare delivery, Long COVID, Winter pressures

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Active

CCU072: Influence of COVID-19 on British burden of cardiovascular disease

Reference: CCU072

Project lead(s): William Whiteley, University of Edinburgh

Start date:

Topic(s): Healthcare delivery, Inequalities, Multiple conditions, Prediction, Whole population

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CCU073: Impact of COVID-19 on the association between Type 2 diabetes and incidence of cardiovascular diseases

Reference: CCU073

Project lead(s): Stephen Kaptoge, University of Cambridge

Start date:

Topic(s):

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CCU069: RARE-CVD-COVID: To understand COVID-19 impact on intersectional disparity in rare versus common cardiometabolic disease, including diabetes

Reference: CCU069

Project lead(s): Sara Khalid, University of Oxford

Start date:

Topic(s): Diabetes, Inequalities, Multiple conditions, Rare diseases, Whole population

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CCU068: The impact of vaccination on the excess clinical risks of COVID-19 in patients with congenital heart disease

Reference: CCU068

Project lead(s): Simon Williams & Bernard Keavney, University of Manchester

Start date:

Topic(s): Congenital heart disease, COVID vaccination, Multiple conditions, Whole population

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Active

CCU066: Changes in acute cardiac care of patients with reduced kidney function during the COVID-19 pandemic.

Reference: CCU066

Project lead(s): David Adlam, University of Leicester & Dorothea Nitsch, LSHTM & Patrick Bidulka, University of Leicester/LSHTM

Start date:

Topic(s): Heart attack, Kidneys, Multiple conditions, Myocardial infarction, Treatments, Whole population

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Active

CCU064: Impact of Covid-19 clinical care pathway changes on gestational diabetes incidence and pregnancy outcomes in England.

Reference: CCU064

Project lead(s): Rebecca Reynolds, University of Edinburgh

Start date:

Topic(s): Diabetes, Healthcare delivery, Inequalities, Pregnancy, Whole population

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Active

CCU063: The effect of COVID-19 on maternal and paediatric health among individuals who require an interpreter in England: from preconception to adolescence

Reference: CCU063

Project lead(s): Robert Aldridge, University College London

Start date:

Topic(s): Children and young people, Healthcare delivery, Inequalities, Pregnancy

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On hold

CCU061: Treatment patterns in COVID-19 in people in England.

Reference: CCU061

Project lead(s): Jennifer Quint, Imperial College London

Start date:

Topic(s): Healthcare delivery, Inequalities, Whole population

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CCU056: Socio-demographic make-up of patients undergoing surgical and transcatheter aortic valve intervention in England and the impact of COVID on this

Reference: CCU056

Project lead(s): Anvesha Singh, Iain Squire et al, University of Leicester

Start date:

Topic(s): Healthcare delivery, Inequalities, Treatments, Whole population

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Active

CCU053: Risks and benefits of treatment with SGLT2 inhibitors and the impact of intercurrent illness with COVID-19.

Reference: CCU053

Project lead(s): Ewan Pearson and Huan Wang, University of Dundee & Reecha Sofat, University of Liverpool

Start date:

Topic(s): Diabetes, Treatments

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Active

CCU052: An observational retrospective cohort study describing the changing epidemiology pre, during and post COVID-19 of asthma, interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD) in England.

Reference: CCU052

Project lead(s): Jennifer Quint, Imperial College London

Start date:

Topic(s): Healthcare delivery, Inequalities, Lungs, Whole population

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Complete

CCU051: Unvaccination and under-vaccination against SARS-CoV-2 in the United Kingdom

Reference: CCU051

Project lead(s): Angela Wood and Genevieve Cezard, University of Cambridge

Start date:

Topic(s): COVID vaccination, Healthcare delivery, Inequalities, Whole population

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Active

CCU049: Healthcare utilisation in individuals with Long Covid

Reference: CCU049

Project lead(s): Amitava Banerjee, University College London

Start date:

Topic(s): Health economics, Healthcare delivery, Long COVID

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On hold

CCU048: COVID-19 infection, vaccination and psychosis risk.

Reference: CCU048

Project lead(s): Dominic Oliver, King's College London

Start date:

Topic(s): COVID vaccination, Mental health

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On hold

CCU047: The impact of COVID-19 on health equality, outcomes and mortality in people with epilepsy in England

Reference: CCU047

Project lead(s): Richard Chin, University of Edinburgh & Owen Pickrell, Swansea University.

Start date:

Topic(s): Epilepsy, Healthcare delivery, Inequalities, Whole population

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Active

CCU046: Severe mental illness and receipt of acute cardiac care and mortality following myocardial infarction

Reference: CCU046

Project lead(s): Caroline Jackson, University of Edinburgh

Start date:

Topic(s): Healthcare delivery, Heart attack, Inequalities, Mental health, Myocardial infarction, Whole population

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Active

CCU045: The impact of COVID-19 on heart failure epidemiology, quality of care and outcomes across primary and secondary care.

Reference: CCU045

Project lead(s): Theresa McDonagh and Antonio Cannata, King’s College London

Start date:

Topic(s): Healthcare delivery, Heart failure, Whole population

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On hold

CU044: Shielding and COVID-19 outcomes

Reference: CCU044

Project lead(s): Deborah Lawlor and Mira Hidajat, University of Bristol

Start date:

Topic(s): Healthcare delivery, Inequalities, Whole population

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Active

CCU043: Investigating new onset diabetes following COVID-19 infection.

Reference: CCU043

Project lead(s): Kamlesh Khunti and Cameron Razieh, University of Leicester

Start date:

Topic(s): Diabetes, Whole population

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CCU040: Investigating why some people with diabetes have a greater risk of becoming seriously unwell or dying with COVID-19

Reference: CCU040

Project lead(s): Adrian Heald, University of Manchester

Start date:

Topic(s): Diabetes, Healthcare delivery, Inequalities

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On hold

CCU039: Greater Manchester Vaccine Equity Study

Reference: CCU039

Project lead(s): Ruth Watkinson, University of Manchester

Start date:

Topic(s): COVID vaccination, Healthcare delivery, Inequalities

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Active

CCU038: Evaluating the impact of COVID-19 on critical care outcomes

Reference: CCU038

Project lead(s): Chris Tomlinson, UCL

Start date:

Topic(s): Healthcare delivery, Treatments

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Active

CCU037: Improving methods to minimise bias in ethnicity data for more representative and generalisable models, using CVD in COVID-19 as an example

Reference: CCU037

Project lead(s): Sara Khalid, University of Oxford

Start date:

Topic(s): Inequalities, Model, Prediction, Whole population

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Active

CCU036: The impact of previous exposure to COVID-19 and the safety of COVID-19 vaccination for fertility and pregnancy outcomes

Reference: CCU036

Project lead(s): Luisa Zuccolo, University of Bristol

Start date:

Topic(s): COVID vaccination, Healthcare delivery, Pregnancy

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Complete

CCU035: Are people with COVID-19 and pre-existing respiratory disease at higher risk of future cardiovascular and thromboembolic events?

Reference: CCU035

Project lead(s): Jennifer Quint, Imperial College London

Start date:

Topic(s): Blood clots, Heart attack, Lungs, Model, Multiple conditions, Prediction, Stroke, Thrombosis

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On hold

CCU034: Impacts of COVID-19 on sight-threatening ocular disease

Reference: CCU034

Project lead(s): Reecha Sofat, University of Liverpool

Start date:

Topic(s): Healthcare delivery, Prediction, Sight loss

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Active

CCU032: The effect of COVID-19 on heart failure subtypes

Reference: CCU032

Project lead(s): Kazem Rahimi and Mohammad Mamouei, University of Oxford

Start date:

Topic(s): Healthcare delivery, Heart failure, Whole population

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On hold

CCU031: Evaluation of cardiotonic steroids use and COVID-19 outcomes

Reference: CCU031

Project lead(s): Gareth Williams, King's College London

Start date:

Topic(s): Treatments

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Active

CCU030: Examining potential factors underlying the increased risk of severe COVID-19 experienced by people with intellectual and developmental disabilities

Reference: CCU030

Project lead(s): Craig Melville, University of Glasgow

Start date:

Topic(s): Inequalities, Multiple conditions

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Active

CCU029: Child hospital admission with COVID-19 - risk factors, risk groups and NHS care utilisation

Reference: CCU029

Project lead(s): Kate Brown, GOSH and UCL

Start date:

Topic(s): Children and young people, Healthcare delivery, Inequalities

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Active

CCU028: Coronary revascularisation and outcomes before and after the COVID-19 pandemic

Reference: CCU028

Project lead(s): Colin Berry, University of Glasgow

Start date:

Topic(s): Health economics, Healthcare delivery, Treatments, Whole population

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On hold

CCU025: Has COVID-19 affected the use of guideline directed medical therapy following coronary artery bypass grafting?

Reference: CCU025

Project lead(s): Salil Deo, University of Glasgow

Start date:

Topic(s): Healthcare delivery, Heart attack, Stroke, Treatments

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Complete

CCU024: CovPall-Connect. Evaluation of how palliative and end of life care teams have responded to COVID-19

Reference: CCU024

Project lead(s): Irene Higginson and Mevhibe Hocaoglu, King’s College London

Start date:

Topic(s): Healthcare delivery, Inequalities

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Active

CCU023: Repurposing medicines used to treat CVD risk to prevent COVID-19

Reference: CCU023

Project lead(s): Reecha Sofat, University of Liverpool and John Overington, Medicines Discovery Catapult

Start date:

Topic(s): COVID vaccination, Treatments

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Active

CCU022: Genomics of multimorbidity and CVD associated with susceptibility to COVID-19 infection and complications

Reference: CCU022

Project lead(s): Michael Inouye, University of Cambridge

Start date:

Topic(s): Inequalities, Model, Multiple conditions, Prediction

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On hold

CCU021: Research into the longer term effects of COVID-19 in non-hospitalised individuals

Reference: CCU021

Project lead(s): Nishi Chaturvedi, UCL

Start date:

Topic(s): Healthcare delivery, Long COVID

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Complete

CCU020: Evaluation of antithrombotic use and COVID-19 outcomes

Reference: CCU020

Project lead(s): Alex Handy, UCL

Start date:

Topic(s): Atrial fibrillation, Blood clots, Stroke, Thrombosis, Treatments, Whole population

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Active

CCU019: Identification and personalised risk prediction for severe COVID-19 in patients with rare disorders impacting cardiovascular health

Reference: CCU019

Project lead(s): Honghan Wu, UCL

Start date:

Topic(s): Healthcare delivery, Inequalities, Prediction, Rare diseases, Whole population

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Active

CCU018: COVID infection during pregnancy on cardiovascular disease and related risk factors

Reference: CCU018

Project lead(s): Elena Raffetti, University of Cambridge

Start date:

Topic(s): COVID vaccination, Healthcare delivery, Pregnancy

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Active

CCU016: Cardiovascular and cerebrovascular diseases related to antipsychotic prescribing in patients with dementia during the COVID-19 pandemic

Reference: CCU016

Project lead(s): Tim Wilkinson, University of Edinburgh

Start date:

Topic(s): Dementia, Healthcare delivery, Heart attack, Stroke, Treatments

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Active

CCU014: Assessing the impact of COVID-19 on clinical pathways using a medicines approach

Reference: CCU014

Project lead(s): Reecha Sofat, University of Liverpool

Start date:

Topic(s): Healthcare delivery, Model, Treatments

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Active

CCU013: High-throughput electronic health record phenotyping approaches

Reference: CCU013

Project lead(s): Spiros Denaxas, UCL

Start date:

Topic(s): Long COVID, Phenotyping, Whole population

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Active

CCU010: In people with CVD and COVID-19, what is the influence of multi-morbidity on risk of poorer outcomes?

Reference: CCU010

Project lead(s): Claire Lawson, University of Leicester

Start date:

Topic(s): Inequalities, Multiple conditions, Prediction

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Complete

CCU008: Evaluating impact of COVID-19 pandemic on the prevalence and management of risk factors

Reference: CCU008

Project lead(s): Naveed Sattar, University of Glasgow

Start date:

Topic(s): Healthcare delivery, Inequalities, Model

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Active

CCU007: Impact of COVID-19 pandemic on heart disease patients undergoing cardiac surgery

Reference: CCU007

Project lead(s): Massimo Caputo, Gianni Angelini, Deborah Lawler, Shrubhra Sinha, Tim Dong, University of Bristol and Kate Brown, GOSH and UCL

Start date:

Topic(s): Children and young people, Congenital heart disease, Healthcare delivery, Heart disease, Treatments

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Active

CCU005: Data management and analysis records

Reference: CCU005

Project lead(s): Angela Wood, University of Cambridge

Start date:

Topic(s): Inequalities, Methodologies, Whole population

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Active

CCU004: COVID and cardiovascular disease risk prevention

Reference: CCU004

Project lead(s): Angela Wood, University of Cambridge

Start date:

Topic(s): Methodologies, Model, Prediction

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Active

CCU003: Direct and indirect effects of the COVID-19 pandemic in individuals with cardiovascular disease

Reference: CCU003

Project lead(s): Amitava Banerjee, UCL

Start date:

Topic(s): Healthcare delivery, Model, Prediction

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Active

CCU002: SARS-CoV-2 infection and vaccination and the risk of vascular events

Reference: CCU002

Project lead(s): William Whiteley, University of Edinburgh

Start date:

Topic(s): COVID vaccination, Inequalities

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Active

CCU001: Investigating the effects of angiotensin converting enzyme inhibitors and angiotensin receptor blockers on COVID-19 outcomes

Reference: CCU001

Project lead(s): Jonathan Sterne, University of Bristol

Start date:

Topic(s): Blood pressure, Hypertension, Treatments, Whole population

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