Data provenance and integrity of health-care systems data for clinical trials. The Lancet

Background: The need to run clinical trials quickly and efficiently is well recognised, none more so than during the push to find life-saving treatments and preventative measures for COVID-19. Late phase clinical trials can take many years and are expensive, due to the immense efforts necessary to deliver them. There are various ways in which the conduct of clinical trials could be improved, one is through judicious use of data already collected in health-care interactions.