People with autoimmune rheumatic diseases, where the immune system attacks its own body, are more likely to have heart attacks and other cardiovascular (CV) diseases than the general population. Idiopathic inflammatory myopathy (IIM) is a rare autoimmune disease where both… Read more

COVID-19 infection (also known as Covid, or severe acute respiratory syndrome coronavirus 2 infection) is mostly mild in children and young people. When someone continues to have symptoms weeks after their COVID-19 infection, this is known as long-COVID. Previous… Read more

Who gets ill, when, and with which diseases and outcomes, are key questions for individuals, clinicians and healthcare systems. The COVID-19 pandemic highlighted this, with a need to identify vulnerable individuals to prioritise interventions such as vaccination. Many models were… Read more

People with severe mental illnesses (SMI) such as schizophrenia and bipolar affective disorders have a life expectancy 15-20 years lower than the general population, with two thirds of deaths from preventable chronic conditions such as cardiovascular and cerebrovascular disease,… Read more

This project aims to improve the design of clinical studies of intracerebral haemorrhage (ICH), a type of stroke caused by bleeding in the brain. It’s important that sufficient numbers of people take part in a… Read more

The NHS has created a talking therapy service called Improving Access to Psychological Therapies (IAPT) to help people with depression and anxiety. IAPT has recently been offered to people with long-term physical disorders that have depression and anxiety. We… Read more

An estimated 14 million people in England are living with two or more chronic conditions, referred to Multiple Long-Term Conditions (MLTC). We know that people living with MLTC have a higher risk of being admitted to hospital and of dying… Read more

COVID-19 infection may become an annual winter virus and follow a clear seasonal pattern, like influenza. Environmental factors, such as extremes in temperature and pollution, could make it easier for the COVID-19 infection to increase the chances of getting… Read more